GW501516 (Cardarine) CAS:317318-70-0
Product Details:
Place of Origin: | CHINA |
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Brand Name: | Hezhong |
Certification: | ISO9001 |
Model Number: | GW501516 CAS:317318-70-0 |
Payment & Shipping Terms:
Minimum Order Quantity: | 10g |
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Price: | negotiable |
Packaging Details: | foil bag or as required |
Delivery Time: | 3-5 work days |
Payment Terms: | T/T, Western Union, MoneyGram, Bitcoin |
Supply Ability: | 100kg/month |
CAS 317318-70-0 Prohormones Steroids Powder SARMS GW501516 / Cardarine / GSK-516
General information:
English name: 2- (4 - ((2- (4- (Trifluoromethyl) phenyl) -5-methyl thiazol-4-yl) methylthio) -2-methylphenoxy) acetic acid
English Name: GW 501516; GW501516; Acetic acid, (2-methyl-4 - (((4-methyl-2- (4- (trifluoromethyl) phenyl) -5-thiazolyl) methyl) thio) phenoxy) -; {2 -methyl-4 - [({4-methyl-2- [4- (trifluoromethyl) phenyl] -1,3-thiazol-5-yl} methyl) sulfanyl] phenoxy} acetic acid; GW-501516
CAS: 317318-70-0
Formula: C21H18F3NO3S2
Molecular Weight: 453.4977
InChI: InChI = 1 / C21H18F3NO3S2 / c1-12-9-16 (7-8-17 (12) 28-10-19 (26) 27) 29-11-18-13 (2) 25-20 (30- 18) 14-3-5-15 (6-4-14) 21 (22,23) 24 / h3-9H, 10-11H2,1-2H3, (H, 26,27)
Molecular Structure: 2- (4 - ((2- (4- (trifluoromethyl) phenyl) -5-methyl-thiazol-4-yl) methyl) -2-methylphenoxy) acetic acid 317318-70-0
Density: 1.426g / cm3
Boiling point: 584.543 ° C at 760 mmHg
Flash Point: 307.321 ° C
Vapor Pressure: 0mmHg at 25 ° CC
Assay:99%
Appearance: White crystalline powder
GW501516 Usage:
GW501516 (also known as GW-501,516, GW1516, GSK-516 and Endurobol)is a PPARδ receptor.
It activates the same pathways activated through exercise, including PPARδ and AMP-activated protein kinase. It had been investigated as a potential treatment for obesity, diabetes, dyslipidemia and cardiovascular disease. GW501516 has a synergistic effect when combined with AICAR: the combination has been shown to significantly increase exercise endurance in animal studies more than either compound .
An experimental drug meant to control lipids and increase the level of HDL, or good cholesterol, in the bloodstream. A cell-permeable, thiazolyl compound that acts as a potent, high affinity, PPARδ agonist.
Exhibits selectivity for PPARδ compared to PPARα and PPARγ. Does not exibit any activity against other nuclear or non-nuclear receptors. Reported to increase cholesterol efflux and ABAC1 expression in macrophages, fibroblasts, and intestinal cells.
GW501516 Function:
(1) GW-501516 (GW1516, Endurobol or GSK-516) acts as a PPAR-β modulator. GW 501516 activates AMP-activated protein kinase and stimulates glucose uptake in skeletal muscle tissue, and GW-501516 has been demonstrated to reverse metabolic abnormalities in obese men with pre-diabetic metabolic syndrome, most likely by stimulating fatty acid oxidation. It has been proposed as a potential treatment for obesity and related conditions, especially when used in conjunction with a synergistic compound AICAR, as the combination has been shown to significantly increase exercise endurance in animal studies.
(2) GW50156 regulates fat burning through a number of mechanisms. It increases glucose uptake in skeletal muscle tissue and increases muscle gene expression, especially genes involved in preferential lipid utilization. This shift changes the body's metabolism to favor burning fat for energy instead of carbohydrates or muscle protein, potentially allowing clinical application for obese patients to lose fat effectively without experiencing muscle catabolism or the effects and satiety issues associated with low blood sugar. GW-501516 also increases muscle mass, which improved glucose tolerance and reduced fat mass accumulation even in mice fed a very high fat diet, suggesting that GW-501516 may have a protective effect against obesity.
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Advantage:
1. Method of Analysis for testing our materials are validated to give the re-producible results
2. All the analytical test procedures and manufacturing procedures are well documented and revision is undertaken as per specified protocol.
3. Trend analysis of purified water and final products are maintained.
4. Stability study is a very important area of quality assuance.
5. Paid orders are processed and despatched the same day and delivered within 5-8 working days worldwide.
6. For your convenience, we use discreet packaging and orders are delivered by post and our delivery success rate is 98%.
7. Should you not receive your order for any reason after 20 working days, please contact us where we will be able to assist you locating your order and if it appears tobe lost in the post, we then will then re-send you a replacement immediately.
Packaging and delivery:
1. Mass stock, to make sure delivery promptly every day when the payment is done.
2. Having been engaged in this field for years, we have sophisticated and professional logistics department, which can guarantee safe and speedy delivery.
3. Well-trained and disciplined packing team which is professional enough to provide you a safe package. It also avoid a lot of emergency happen during the delivery so that high customs pass is guaranteed. Unique ways to ship 10grams to 20 kilograms powders(or 100ml to 30 Liter liquids) at one time to your destination.
4. Packing pictures and tacking code are provided within 12 hours as soon as receiving the payment. Updated tracking information will be provided every other day just for you can hold a palm of your package.
5. Perfect after-sale service: Any questions or problems happened after receiving the product, please feel free to contact us. Problems would be solved immediately.
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