GW501516 (Cardarine) CAS:317318-70-0

GW501516

Product Details:

Place of Origin:CHINA
Brand Name:Hezhong
Certification:ISO9001
Model Number:GW501516 CAS:317318-70-0

Payment & Shipping Terms:

Minimum Order Quantity:10g
Price:negotiable
Packaging Details:foil bag or as required
Delivery Time:3-5 work days
Payment Terms:T/T, Western Union, MoneyGram, Bitcoin
Supply Ability:100kg/month
Order Inquiry

CAS 317318-70-0 Prohormones Steroids Powder SARMS GW501516 / Cardarine / GSK-516

 

General information:

 
 English name: 2- (4 - ((2- (4- (Trifluoromethyl) phenyl) -5-methyl thiazol-4-yl) methylthio) -2-methylphenoxy) acetic acid
English Name: GW 501516; GW501516; Acetic acid, (2-methyl-4 - (((4-methyl-2- (4- (trifluoromethyl) phenyl) -5-thiazolyl) methyl) thio) phenoxy) -; {2 -methyl-4 - [({4-methyl-2- [4- (trifluoromethyl) phenyl] -1,3-thiazol-5-yl} methyl) sulfanyl] phenoxy} acetic acid; GW-501516
CAS: 317318-70-0
Formula: C21H18F3NO3S2
Molecular Weight: 453.4977
InChI: InChI = 1 / C21H18F3NO3S2 / c1-12-9-16 (7-8-17 (12) 28-10-19 (26) 27) 29-11-18-13 (2) 25-20 (30- 18) 14-3-5-15 (6-4-14) 21 (22,23) 24 / h3-9H, 10-11H2,1-2H3, (H, 26,27)
Molecular Structure: 2- (4 - ((2- (4- (trifluoromethyl) phenyl) -5-methyl-thiazol-4-yl) methyl) -2-methylphenoxy) acetic acid 317318-70-0
Density: 1.426g / cm3
Boiling point: 584.543 ° C at 760 mmHg
Flash Point: 307.321 ° C
Vapor Pressure: 0mmHg at 25 ° CC
Assay:99%
Appearance: White crystalline powder

 

GW501516 Usage:


GW501516 (also known as GW-501,516, GW1516, GSK-516 and Endurobol)is a PPARδ receptor.
It activates the same pathways activated through exercise, including PPARδ and AMP-activated protein kinase. It had been investigated as a potential treatment for obesity, diabetes, dyslipidemia and cardiovascular disease. GW501516 has a synergistic effect when combined with AICAR: the combination has been shown to significantly increase exercise endurance in animal studies more than either compound .
An experimental drug meant to control lipids and increase the level of HDL, or good cholesterol, in the bloodstream. A cell-permeable, thiazolyl compound that acts as a potent, high affinity, PPARδ agonist.
Exhibits selectivity for PPARδ compared to PPARα and PPARγ. Does not exibit any activity against other nuclear or non-nuclear receptors. Reported to increase cholesterol efflux and ABAC1 expression in macrophages, fibroblasts, and intestinal cells. 
 

GW501516  Function:

(1) GW-501516 (GW1516, Endurobol or GSK-516) acts as a PPAR-β modulator. GW 501516 activates AMP-activated protein kinase and stimulates glucose uptake in skeletal muscle tissue, and GW-501516 has been demonstrated to reverse metabolic abnormalities in obese men with pre-diabetic metabolic syndrome, most likely by stimulating fatty acid oxidation. It has been proposed as a potential treatment for obesity and related conditions, especially when used in conjunction with a synergistic compound AICAR, as the combination has been shown to significantly increase exercise endurance in animal studies.
 
(2) GW50156 regulates fat burning through a number of mechanisms. It increases glucose uptake in skeletal muscle tissue and increases muscle gene expression, especially genes involved in preferential lipid utilization. This shift changes the body's metabolism to favor burning fat for energy instead of carbohydrates or muscle protein, potentially allowing clinical application for obese patients to lose fat effectively without experiencing muscle catabolism or the effects and satiety issues associated with low blood sugar. GW-501516 also increases muscle mass, which improved glucose tolerance and reduced fat mass accumulation even in mice fed a very high fat diet, suggesting that GW-501516 may have a protective effect against obesity.

 

Related products we provide

 

Adrafinil
to increases the brain neurotransmitter, hypocretin
Aniracetam
to improve learning and memory, increase perception, reduce anxiety and increase reflexes
Carphedon
anti-amnesic, antidepressant,anticonvulsant, antipsychotic, anxiolytic, andmemory enhancement effects
Centrophenoxine
shown to improve memory, have a mentally stimulating effect, and improve general cognition for elder patients
Coluracetam
potential use in prevention and treatment of ischemicretinopathy and retinal andoptic nerve injury and a potential therapeutic drug for schizophrenia
IDRA-21
shown to be valuable in memory improvement, cognitive enhancement, stimulation, and reversing cognitive deficits
Modafinil
to improve ability to focus in duration and intensity, analytic capabilities, memory recall and rententio, mood and well-being.
Noopept
to offer many benefits in terms of improving memory, learning capacity, focus, and concentration
NSI-189
to stimulate neurogenesis of human hippocampal stem cells in vitro and in vivo
Oxiracetam
highly effective at increasing attention span, memory, mental energy and cognitive processing
PRL-8-53
to improve learning and memory
Sunifiram
as an ampakine because it gains its effectiveness through the increasing glycine receptor binding
Unifiram
to improve learning and memory, increase perception, reduce anxiety and increase reflexes
Vinpocetine
shown to be valuable in protecting heart, visual, and hearing functions, among other benefits

 

Advantage:
1. Method of Analysis for testing our materials are validated to give the re-producible results
2. All the analytical test procedures and manufacturing procedures are well documented and revision is undertaken as per specified protocol.
3. Trend analysis of purified water and final products are maintained.
4. Stability study is a very important area of quality assuance.
5. Paid orders are processed and despatched the same day and delivered within 5-8 working days worldwide.
6. For your convenience, we use discreet packaging and orders are delivered by post and our delivery success rate is 98%.
7. Should you not receive your order for any reason after 20 working days, please contact us where we will be able to assist you locating your order and if it appears tobe lost in the post, we then will then re-send you a replacement immediately.
 
Packaging and delivery:

1. Mass stock, to make sure delivery promptly every day when the payment is done.
2. Having been engaged in this field for years, we have sophisticated and professional logistics department, which can guarantee safe and speedy delivery.
3. Well-trained and disciplined packing team which is professional enough to provide you a safe package. It also avoid a lot of emergency happen during the delivery so that high customs pass is guaranteed. Unique ways to ship 10grams to 20 kilograms powders(or 100ml to 30 Liter liquids) at one time to your destination.
4. Packing pictures and tacking code are provided within 12 hours as soon as receiving the payment. Updated tracking information will be provided every other day just for you can hold a palm of your package.
5. Perfect after-sale service: Any questions or problems happened after receiving the product, please feel free to contact us. Problems would be solved immediately.
 

Please send your inquiry directly to us


Send