|Place of Origin:||China|
Payment & Shipping Terms:
|Minimum Order Quantity:||10 vials|
|Packaging Details:||Original Kits or as your reqirements|
|Delivery Time:||After receipt of your payment|
|Payment Terms:||Western Union,Money Gram or T/T|
|Supply Ability:||5000 Vial per month|
99% Oxytocin Raw Hormone Powder Lyophilized Powder CAS 50-56-6 hgh PT-141
Oxytocin is a synthetic form of naturally occurring hypothalamic hormone. After secretion, oxytocin is released into the blood circulation by the pituitary gland. The polypeptide molecule contains 9 amino acids. In 1953, oxytocin was first synthesized by the scientists, and it is one earliest sequenced peptide molecules. The prime role of oxytocin is neuromodulation in the brain. Additionally, the hormone tends to increase trust, human bonding, empathy, romantic attraction and decrease fear. Research studies are being conducted to investigate the role in human behaviors including social and emotional recognition, pair bonding, anxiety and sexual orgasm. The molecular mass of the synthetic hormone is 1007.9 Daltons and molecular formula is C43H66N12O12S2.
Oxytocin is synthesized as an active precursor from the popular OXT gene, the structure is similar to vasopressin, and however they differ in the sequence by two amino acids. Vasopressin and oxytocin are the only known human hormones, which acts distally, although others act locally such as dynorphin and corticotropin-releasing hormone. Oxytocin receptors are a G-coupled protein receptor, which requires cholesterol and magnesium ions to function optimally. Research reveals that oxytocin has trust inducing properties and it can help individuals who suffer from social anxieties and mood disorders. Oxytocin has a similar structure to vasopressin , however vasopressin has antagonistic properties to the hormone production. Recent research papers show that oxytocin may have a role in autism, it can be effective in treating affilliative and repetitive behaviors seen in autism. However, the hormone is destroyed in the gastric tract, it has a half-life of 3 minutes, and it does not enter the brain because of the blood brain barrier. In the hypothalamic gland, the hormone is biosynthesized in the magnocellular neurosecretory cells located on the paraventricular nuclei and supraoptic nuclei.
Injected oxytocin analogues are used for labor induction and to support labor in case of difficult parturition. It has largely replaced as the principal agent to increase uterine tone in acute postpartum hemorrhage. Oxytocin is also used in veterinary medicine to facilitate birth and to stimulate milk release. The tocolyticagent atosiban (Tractocile) acts as an antagonist of oxytocin receptors; this drug is registered in many countries to suppress premature labor between 24 and 33 weeks of gestation. It has fewer side effects than drugs previously used for this purpose (ritodrine).
Usage and dosage
Odinopoeia or oxytocin intravenous drip, once the 2.5 - 5 units, with Sodium Chloride Injection diluted to each 1ml contains 0.01 units. Intravenous drip of the beginning of every minute of not more than 0.001 to 0.002 units, each 15 - 30 minutes increased 0.001 to 0.002 units, to achieve the contractions and normal childbirth is similar, the fastest per minute of not more than 0.02 units, usually 0.002 to 0.005 units per minute.
Control postpartum hemorrhage per minute intravenous drip of 0.02 - 0.04 units, expulsion of the placenta after intramuscular injection of 5 to 10 units.
Lactogenic just before a 2 - 3 minutes, with nasal drops a 3 drop, drop into one side or both sides of the nostril.
Preparation and specification : oxytocin injection (1) 0.5ml:2.5 units (2) 1ml:5 (3) 1ml units 10 units;
Oxytocin nasal drops 1ml:40 units. The induction of labor or prenatal uterine atony: in 2.5-5 units in 500ml 5% glucose for intravenous drip slowly (10-30 drops / minute), maximum time 20 units. (2). Prevention of postpartum hemorrhage: intramuscular injection of 5-10 on each unit, or 5% glucose solution for intravenous drip.
The main contraindication, heart disease, a caesarean history and more than three fetal maternal disable.
Oxytocin Chemical Profile
Cas No.: 50-56-6
EINECS : 200-048-4
Molecular Formula: C43H66N12O12S2
Purity (HPLC): 98.0%min.
Appearance: White powder
Single Impurity (HPLC): 1.0%max
Amino Acid Composition: ±10% of theoretical
Peptide Content (N%): >80.0%
Water Content(Karl Fischer): <6.0%
Acetate Content(HPIC): <12.0%
Mass Balance: 95.0~105.0%
Grade : Pharmaceutical Grade
Storage: Closed, below 2 ~ 8ºC preservation
Manufacturer : Hezhong
Usage : For induction of labor, postpartum oxytocin, and abortion due to uterine atony or retraction caused by the bad uterus bleeding; understand the placental function reserve (oxytocin challenge test); nasal drops can promote milk ejection.
1. Method of Analysis for testing our materials are validated to give the re-producible results
2. All the analytical test procedures and manufacturing procedures are well documented and revision is undertaken as per specified protocol.
3. Trend analysis of purified water and final products are maintained.
4. Stability study is a very important area of quality assuance.
5. Paid orders are processed and despatched the same day and delivered within 5-8 working days worldwide.
6. For your convenience, we use discreet packaging and orders are delivered by post and our delivery success rate is 98%.
7. Should you not receive your order for any reason after 20 working days, please contact us where we will be able to assist you locating your order and if it appears tobe lost in the post, we then will then re-send you a replacement immediately.
Packaging and delivery:
1. Mass stock, to make sure delivery promptly every day when the payment is done.
2. Having been engaged in this field for years, we have sophisticated and professional logistics department, which can guarantee safe and speedy delivery.
3. Well-trained and disciplined packing team which is professional enough to provide you a safe package. It also avoid a lot of emergency happen during the delivery so that high customs pass is guaranteed. Unique ways to ship 10grams to 20 kilograms powders(or 100ml to 30 Liter liquids) at one time to your destination.
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