CJC 1295 NO DAC 2mg

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CJC-1295 Without DAC Human Growth Hormone Polypeptide Hormone CJC-1295 no-DAC

General information:

CJC-1295, a modified form of GRF 1-29 NO DAC, is a peptide hormone that contains 29 amino acids. Since the 2000’s, the compound has been studied to explore the lipolytic properties, particularly the visceral fat elimination. The compound is able to conjugate with serum albumin, thereby increasing the half-life and therapeutic potential. CJC-1295 stimulates the pituitary gland, and promotes protein biosynthesis. Research suggests CJC-1295 might increase secretion of growth hormones and IGF-1 but not prolactin. The molecular weight and formula of the compound is 3367.979 and C152H252N44O42, respectively.

The modified GRF 1-29 is a modified version of the growth hormone releasing factor with Gln, Ala, Leu, and D-Ala substituted on position 8, 15, 27, and 2, respectively. The substitution is important in creating a more stable peptide and each substitution plays a key role. Substitution at position 27 prevents the oxidation of methionine, position 15 enhances the bioactivity of the peptide, and position 8 reduces asparagines rearrangement while position 2 prevents the DPP-IV cleavage process. CJC-1295 and CJC-1295 DAC are both analogs of the growth hormone releasing hormone; their mode of action is similar, however, the main difference between the two peptides is the half-life. Many scientists consider Mod GRF 1-29 to be more natural because it stimulates the HGH release in a pulsatile manner. One of the studies on CJC -1295 indicates that the peak shown by the hormone is preferable for the immediate increase in GH, however a combined therapy is mostly recommended because it can balance the release of the hormone while inhibiting somatostatin, thereby increasing GH per somatotrope.

Applications:

Modified Growth Releasing Factor aminos 1-29, usually referred to as Modified GRF (1-29) or “ModGRF(1-29),” also known as CJC-1295 without DAC, is a synthetic analog of the endogenous peptide signaling hormone Growth Hormone Releasing Hormone (GHRH). Endogenously produced GHRH has 44 amino acids in its chain structure. A truncated synthetic form of GHRH called Sermorelin or GRF 1-29 has 29 amino acids; Modified GRF (1-29) is further changed in that it has four substituted aminos in its chain that serve the purposes of preventing degradation and oxidation in manufacture and transport as well as in vivo, while also increasing binding affinity to the GHRH receptors.

Modified GRF (1-29) is not CJC-1293 nor should it be referred to as such. Modified GRF (1-29) is identical to the portion of CJC-1295 DAC that is not bound to MPA, minus the lysine. The presence of lysine in a literal “CJC without DAC” in the absence of MPA would have the opposite effect of DAC: it would drastically reduce the active life of the peptide to that of Sermorelin. Modified GRF (1-29) is the same as CJC-1295 with out DAC.

CJC-1295 DAC and CJC-1295 (also known as Modified GRF 1-29) are both Releasing Hormones (GHRH). Their action in the human body is identical but the difference between the two peptides are the span of the half-life. Modified GRF 1-29 and Sermorelin have a very short acting half-life of about 30 minutes, while CJC-1295 DAC has a half-life that can last up to approximately 8 days. Many a scientist have reported that the short half-life of Sermorelin and Modified GRF 1-29 is considered to be much more natural as they produce a short pulse of Human Growth Hormone.

CJC 1295 HOW TO INJECT:

A subcutaneous injection is preferred. Wash hands and gather materials. Cleanse the top of the vial with an alcohol wipe. Use an insulin syringe to draw the desired dose from the vial. Gently tap /flick the syringe and remove air bubbles. Cleanse the skin site with an alcohol based rub to prevent infection. Pinch the skin to create a fold of subcutaneous fat. Gently insert the needle into the fat, and inject the contents of the syringe. Wipe the injection site with alcohol and dispose of the used syringe in a puncture proof container.

CJC-1295 FLUSH:

CJC-1295 Peptide is generally very well tolerated by most individuals dosing with 100mcg per injection. The most common side effect noted is a head "rush" and throbbing of the temples which may start 10 minutes post injection and lasts up to 20 minutes. This side effect is not serious, and is caused by a release of GABA (gamma-aminobutyric acid, one neurotransmitter) in the brain. Some users take this as a good sign their peptide is working to stimulate HGH release.

IS CJC 1295 BETTER THAN HGH?

Without a doubt, CJC-1295 is better than HGH. CJC-1295 causes an increase in your HGH production and helps to stimulate IGF-1 as well. It is also less expensive than HGH, and produces the same loss of body fat and muscular growth with fewer injections.

CJC-1295 Chemical Profile

Advantage:

1. Method of Analysis for testing our materials are validated to give the re-producible results
2. All the analytical test procedures and manufacturing procedures are well documented and revision is undertaken as per specified protocol.
3. Trend analysis of purified water and final products are maintained.
4. Stability study is a very important area of quality assuance.
5. Paid orders are processed and despatched the same day and delivered within 5-8 working days worldwide.
6. For your convenience, we use discreet packaging and orders are delivered by post and our delivery success rate is 98%.
7. Should you not receive your order for any reason after 20 working days, please contact us where we will be able to assist you locating your order and if it appears tobe lost in the post, we then will then re-send you a replacement immediately.

Packaging and delivery:

1. Mass stock, to make sure delivery promptly every day when the payment is done.
2. Having been engaged in this field for years, we have sophisticated and professional logistics department, which can guarantee safe and speedy delivery.
3. Well-trained and disciplined packing team which is professional enough to provide you a safe package. It also avoid a lot of emergency happen during the delivery so that high customs pass is guaranteed. Unique ways to ship 10grams to 20 kilograms powders(or 100ml to 30 Liter liquids) at one time to your destination.
4. Packing pictures and tacking code are provided within 12 hours as soon as receiving the payment. Updated tracking information will be provided every other day just for you can hold a palm of your package.
5. Perfect after-sale service: Any questions or problems happened after receiving the product, please feel free to contact us. Problems would be solved immediately.

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