Gamma-Butyrolactone (GBL) CAS 96-48-0
|Place of Origin:||CHINA|
|Model Number:||Gamma-Butyrolactone (GBL) CAS 96-48-0|
Payment & Shipping Terms:
|Minimum Order Quantity:||10g|
|Packaging Details:||foil bag or as required|
|Delivery Time:||3-5 work days|
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Pharmaceutical Intermediates gamma butyrolactone/ γ -Butyrolactone GBL Cleaner CAS 96-48-0
γ -Butyrolactone (GBL)
Alias: butyrolactone; GBL, γ-BLO, Gamma Butyrolactone, 1, 4- Butyrolactone, 4-hydroxybutyric acid lactone, gamma-hydroxybutyric acid lactone, and oxolan-2-one
Assay: 99.5%, 99.8%
Melting point: -43.53
Appearance: colorless oily liquid
Category: fine chemical intermediates
Packaging: 200KG / galvanized iron drum or as required
GBL is an important chemical raw material and intermediate for medicine, and also the intermediate of the synthesize N-methyl pyrrolidone, α -pyrrolidone, polyvinyl pyrrolidone, α -acetyl-γ -butyrolactone, methionine and the butyric acid compounds. This product features a strong solubility, and is a good solvent for polyacrylonitrile, epoxy resin, polyvinyl butyral, polyvinyl chloride and its copolymers, and cellulose polymers. In medical industry, it is mainly used in synthesizing cyclopropylamine, etc.
Gamma Butyrolactone is an important chemical raw material and intermediate for medicine, and also the intermediate of the synthesize N-methyl pyrrolidone, α -pyrrolidone, polyvinyl pyrrolidone, α -acetyl-γ -butyrolactone, methionine and the butyric acid compounds. This product features a strong solubility, and is a good solvent for polyacrylonitrile, epoxy resin, polyvinyl butyral, polyvinyl chloride and its copolymers, and cellulose polymers. In medical industry, it is mainly used in synthesizing cyclopropylamine, etc
Gamma-Butyrolactone (γ-butyrolactone or GBL) is a hygroscopic colorless liquid with a weak characteristic odor which is soluble in water. GBL is a common solvent and reagent in chemistry as well as being used as a flavouring, as a cleaning solvent, as a superglue remover, and as a solvent in some wet aluminium electrolytic capacitors. In humans it acts as a prodrug for GHB, and it is used as a recreational intoxicant with effects similar to alcohol.
GBL is a lactone. It is hydrolyzed under basic conditions, for example in a sodium hydroxide solution into sodium gamma-hydroxybutyrate, the sodium salt of gamma-hydroxybutyric acid. Under acidic conditions it forms an equilibrium mixture of both compounds. These compounds then may go on to form a polymer. When treated with a non-nucleophilic base, like lithium diisopropylamide, GBL can become an alpha-carbon nucleophile. The related compound caprolactone can be used to make a polyester in this manner.
GBL is rapidly converted into GHB by paraoxonase (lactonase) enzymes, found in the blood. Animals which lack these enzymes exhibit no effect from GBL. GBL is more lipophilic (fat soluble) than GHB, and so is absorbed faster and has higher bioavailability. Because of these pharmacokinetic differences, GBL tends to be more potent and faster-acting than GHB, but has a shorter duration; whereas the related compound 1,4-butanediol (1,4-B) tends to be slightly less potent, slower to take effect but longer-acting than GHB.
tetrahydrofuran (wt% GC)
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