Melanotan 2 10mg
|Place of Origin:||China|
|Model Number:||Melanotan II|
Payment & Shipping Terms:
|Minimum Order Quantity:||10 vials|
|Packaging Details:||Original Kits or as requirements|
|Delivery Time:||After receipt of your payment|
|Payment Terms:||Western Union,Money Gram or T/T|
|Supply Ability:||8000 Vial per month|
Melanotan II Polypeptide Hormones CAS 121062-08-6 Melanotan 2 Human Growth Hormone MT-2
Melanotan 2 is a man-made version of alpha melanocyte stimulating hormone (MSH), a melanocortin peptide hormone. Melanotan 2 was first synthesized by researchers at the University of Arizona for melanogenesis, and to increase libido effects in men. Melanotan 2 mimics melanogenesis and UV-protective effects of Melanotan 1. However, recent research evidences suggest aphrodisiac effects of Melanotan 2. Due to protective effects against harmful UV rays, Melanotan 2 is being studied as a potential prophylaxis against melanoma (skin cancer). The synthetic chemical is contraindicated for consumption, diagnosis or treatment in humans, and strictly for research purpose only. The molecular weight and formula is 1024.2 and C50H69N15O9, respectively.
Studies indicate that MSH has a considerable effect on appetite, lipid metabolism, and sexual libido via the melanocortin receptors. Melanotan 2 has been under studies to determine its effectives as appetite suppressant, libido enhancing properties and appetite suppressant properties. Moreover, Melanotan 2 has shown efficacy in combating erectile dysfunction and other sexual dysfunction related conditions.Melanotan II has shown to be effective in increasing libido, and has aphrodisiac properties. The hormone is a cyclic heptapeptide analog of alpha MSH. Research indicates that Melanotan 2 activates the central melanocortin, which in turn triggers melanogenesis, and skin tanning occurs. Melanotan II reduces the serum levels of cholesterol and insulin, moreover further studies indicate that it lowers the levels of acetylcholine, a carboxylase expression and in other cases, it inhibited the reduction of palmitoltransferase I mRNA, and carnitine. This shows that the hormone increases cholesterol metabolism and fat catabolism.
Studies show that Melanotan 2 can be effective in treating polymorphous eruption and actinic keratosis, the common skin conditions that are characterized by intolerance to sunlight. Exposure to the sun results in burning sensation, severe sores, itchiness, lumps, dry skin among others. Melanotan 2 cannot treat albinism because the albinos have no melanocortin receptors therefore the hormone will not be able to bind and induce tanning.
If you look hard enough out there, you will find some weird and wonderful dosaging schedules whereby the user calculates their daily dosage by multiplying their bodyweight by a cofactor. Perhaps this approach has been adopted since this has been the method employed in the ongoing clinical studies. Typically, this type of formula would suggest a dose of 1mg of MT-II per day for someone weighing in at a mere 110lb (50kg). The cynical among us might be forgiven for thinking that these formulae are constructed by those with a personal interest in the sale of the product as I believe this to be more than necessary to achieve a great result. Indeed, there are many instances whereby users feel they have become too dark. While I have no problem with a bodyweight dosage scale in principle, I can't help thinking that it's not only unnecessary (particularly for the mathematically challenged), but also avoids the ability to gradually increase dosages from a relatively low level; something which I would advocate to assess individual tolerance levels to side effects, especially in the case of MT-II.
Clinical trials to determine efficacy of the drugs have typically used dosages up to 0.21mg/kg daily for Melanotan (16mg for a 75kg (165lb) individual), and up to 0.03mg/kg daily for Melanotan II (2.25mg for a 75kg (165lb) individual). More typically however, trials have used the dosages of 0.16mg/kg (12mg) and 0.025mg/kg (1.875mg) respectively. At this level of dosage, one such study involving Melanotan indicated the following incidences of side effects from subjects:
Facial Flushing 75%
Injection site reactions 13%
Zero incidence of erections
No change in vital signs or haematological parameters, blood biochemistry (liver and renal function)
As is the case with any drug use, the user is ideally looking to minimise unwanted side effects, whilst still achieving an acceptable outcome. With this in mind, I would suggest that a tapering up of dosages is used in order to assess the individual's personal tolerance to the side effects.
Both MT and MT II can be used for extended periods, whereby there is an initial daily administration of perhaps 2-3 weeks or until desired level of pigmentation has been achieved, followed by a maintenance phase of two injections per week.
Melanotan 2 Chemical Profile
Unit Size :10 mg/vial
Unit Quantity :1 Vial
CAS NO. :121062-08-6
Molecular Formula :C50H69N15O9
Molecular Weight :1024.18
Appearance :White Powder
Identity (ESI-MS) :1024.18±1.0
Source :Chemical Synthesis
Storage :Lyophilized Melanotan II is stable at room temperature for 90 days,however it should be stored in a freezer below -8C for any extended period of time. After reconstituting Melanotan II should be refrigerated at temperatures not to exceed 36 F.
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2. All the analytical test procedures and manufacturing procedures are well documented and revision is undertaken as per specified protocol.
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