Positive Androstenedione CAS:63-05-8 Prohormones Steroids 4-DHEA (4-AD) Androgenic Anabolic Steroids

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Positive Androstenedione CAS:63-05-8 Prohormones Steroids 4-DHEA (4-AD) Androgenic Anabolic Steroids

Quick Detail
Androstenedione
Molecular Formula C19H26O2
Molecular Weight 286.41
CAS Registry Number 63-05-8
EINECS 200-554-5
Melting point 170-173℃
Assay: 98% min.
Appearance: White crystalline powder.
Usage: pharmaceutical material, Steroid hormone, main intermediate for the production of steroidal hormone drugs and contraceptives.

1.What is androstenedione?

Androstenedione is described as a ‘pro-hormone’ because it has few effects itself.  Instead, it is important because of the ability of different parts of the body to convert it into the hormones, testosterone and oestrogen, which exert many effects on the body.

In females, the outer part of the adrenal glands (known as the cortex) and the ovaries release androstenedione into the bloodstream where it is converted to provide around half of all testosterone and almost all of the body’s oestrone, a form of oestrogen.  Although the testes produce large amounts of androstenedione in males, they secrete little of this into the blood and, instead, rapidly convert it into testosterone within the testes.  The adrenal glands also produce androstenedione in men, but this contribution is swamped by the testes’ overwhelming production of the other androgenic hormone, testosterone.  

2 . OverView:

Androstenedione is a hormone produced naturally in the body by the adrenal glands, the ovaries (in women), and the testicles (in men). The body first manufactures DHEA , then turns DHEA into androstenedione, and finally transforms androstenedione into testosterone, the principal male sex hormone. Androstenedione is also transformed into estrogen. It is widely used by athletes who believe that it can build muscle and increase strength.

3. How is androstenedione controlled? 

Due to its secretion from a number of different glands and its often rapid conversion to other hormones, the control of androstenedione within the body is very complex.  However, two key parts of the brain (the hypothalamus and pituitary gland) are known to be important in the control of androstenedione secretion from the testes, ovaries and adrenal cortex.  The release of androstenedione by the adrenal cortex is thought to be related to the pituitary gland’s secretion of a specialised hormone, adrenocorticotropic hormone.  Precisely how adrenocorticotropic hormone and other hormones control the adrenal gland’s production of androstenedione is, however, unclear.  The testes and ovaries are stimulated to release androstenedione by luteinising hormone and follicle stimulating hormone.  These are released from the anterior pituitary gland in response to a hormone signal from the hypothalamus.

4. What happens if I have too little androstenedione?

Boys with too little androstenedione may fail to develop the sexual characteristics associated with puberty, including pubic and body hair, growth of the sexual organs and deepening of the voice.  Similarly, girls may fail to start their periods and may not undergo many of the changes usually seen in puberty.  Additionally, if a male foetus has too little androstenedione, he may be born with abnormal genitalia.  Too little androstenedione in later life would cause the same changes for both men and women as too little testosterone and oestrogen.

5. Sources: 

Androstenedione is not an essential nutrient—your body manufactures it from scratch. It is found in meat and in some plants, but to get a therapeutic dosage, you will need to take supplements.

6. Therapeutic Dosages  

The typical recommended dose of androstenedione is 100 mg 2 times daily with food

 

Androstenedione is said to enhance athletic performance and strength by increasing testosterone production, thereby building muscle. However, in double-blind studies, when androstenedione was given to men, it did not alter total testosterone levels, nor improve sports performance, strength, or lean body mass. 2–7 It did, however, increase estrogen levels, an effect that would not be considered favorable. Curiously, some evidence suggests that androstenedione does raise testosterone levels levels in women; again, this is not likely to produce favorable results, and it could cause harm (see Safety Issues ). 8,11 The most consistent effect of androstenedione is to increase estrogen levels.
 
 
Applications:
 
Androstenedione is a hormone produced naturally in the body by the adrenal glands, the ovaries (in women), and the testicles (in men). The body first manufactures DHEA , then turns DHEA into androstenedione, and finally transforms androstenedione into testosterone, the principal male sex hormone. Androstenedione is also transformed into estrogen.
Androstenedione is widely used by athletes who believe that it can build muscle and increase strength. However, there is no evidence that it works. Furthermore, androstenedione supplements may cause positive urine tests for illegal steroid use, due to the common presence of a contaminant (19-norandrostenedione).
The typical recommended dose of androstenedione is 100 mg 2 times daily with food.

Males*

Females*

Advantage:

1. Method of Analysis for testing our materials are validated to give the re-producible results
2. All the analytical test procedures and manufacturing procedures are well documented and revision is undertaken as per specified protocol.
3. Trend analysis of purified water and final products are maintained.
4. Stability study is a very important area of quality assuance.
5. Paid orders are processed and despatched the same day and delivered within 5-8 working days worldwide.
6. For your convenience, we use discreet packaging and orders are delivered by post and our delivery success rate is 98%.
7. Should you not receive your order for any reason after 20 working days, please contact us where we will be able to assist you locating your order and if it appears tobe lost in the post, we then will then re-send you a replacement immediately.

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1. Mass stock, to make sure delivery promptly every day when the payment is done.
2. Having been engaged in this field for years, we have sophisticated and professional logistics department, which can guarantee safe and speedy delivery.
3. Well-trained and disciplined packing team which is professional enough to provide you a safe package. It also avoid a lot of emergency happen during the delivery so that high customs pass is guaranteed. Unique ways to ship 10grams to 20 kilograms powders(or 100ml to 30 Liter liquids) at one time to your destination.
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