Dapoxetine Hydrochloride CAS 129938-20-1
Product Details:
| Place of Origin: | CHINA |
|---|---|
| Brand Name: | Hezhong |
| Certification: | ISO9001 |
| Model Number: | Dapoxetine Hydrochloride CAS 129938-20-1 |
Payment & Shipping Terms:
| Minimum Order Quantity: | 10g |
|---|---|
| Price: | Negotiable |
| Packaging Details: | foil bag or as required |
| Delivery Time: | 3-5 work days |
| Payment Terms: | T/T, Western Union, MoneyGram, Bitcoin |
| Supply Ability: | 100kg/month |
99%Pure Popular Sex Enhancer Dapoxetine Hydrochloride (CAS 129938-20-1)
General information:
| Product Name | Dapoxetine Hydrochloride |
| Synonyms | (1s)-n,n-dimethyl-3-naphthalen-1-yloxy-1-phenyl-propan-1-amine hydrochloride;DAPOXETINE HCL;DAPOXETINE HYDROCHLORIDE CHEMISTRY PURE 98.5% HPLC ;Rimonabant 75000;(aS)-N,N-Dimethyl-a-[2-(1-naphthalenyloxy)ethyl]benzenemethanamine;LY-21044;((S)-(+)-N,N-Dimethyl-1-phenyl-3-(1-naphthalenyloxy)propanamine hydrochloride);(S)-(+)--N,N-Dimethyl-1-phenyl-3-(1-naphthalenyloxy)propanamine |
| CAS | 129938-20-1 |
| MF | C9H7ClN2O5 |
| MW | 258.62 |
| MP | 175-179°C |
| Product Categories | Intermediates & Fine Chemicals;Pharmaceuticals;Amines;Aromatics;Inhibitors;Dapoxetine Hydrochloride |
| Appearance | Off-white Crystals |
| Purity | 99.61% |
| Usage | 1. Dapoxetine hydrochloride is a short-acting novel selective serotonin reuptake inhibitor marketed for the treatment of premature ejaculation in men. Premature ejaculation (PE) is the most common male sexual disorder, estimated to affect up to 30% of men. 2. A selective serotonin reuptake inhibitor. 3. Selective serotonin reuptake inhibitor (SSRI). |
Descriptions and Applications:
Dapoxetine (dapoxetine) as a new fast SSRI, a short half life, a selective 5 - HT reuptake inhibitor (SSRI), for the treatment of premature ejaculation and erectile dysfunction. Dapoxetine is a selective 5 - HT reuptake inhibitor (SSRI), such drugs widely used to treat depression and related affective disorders.
Dapoxetine, marketed as Priligy (among and other brands) is the first compound developed specially for the treatment of premature ejaculation (PE) in men 18-64 years old. Dapoxetine works by inhibiting the serotonin transporter, increasing serotonin's action at the post synaptic cleft, and as a consequence promoting ejaculatory delay. As a member of selective serotonin reuptake inhibitor (SSRI) family, dapoxetine was initially created as an antidepressant. However, unlike other SSRIs, dapoxetine is absorbed and eliminated rapidly in the body. Its fast acting property makes it suitable for the treatment of PE but not as an antidepressant.
Treat male premature ejaculation and erectile dysfunction. Because lack of specific approval treatment for PE in the US and some other countries, other SSRIs such as fluoxetine, paroxetine, sertraline, fluvoxamine, and citalopram have been used as off label drugs to treat PE.
Waldinger's meta analysis shows that the use of these conventional antidepressants increasing IELT from two to ninefold above base line in comparison of three to eightfold when dapoxetine is used. Dapoxetine, on the other hand, is a fast-acting SSRI. It is rapidly absorbed and eliminated from the body within a few hours. This favorable pharmacokinetics minimizes the risk of the drug's accumulation in the body, and therefore reducing side effects.
What’s the benefits of Dapoxetine Hydrochloride?
1. Dapoxetine Hydrochloride is indicated as a sympathicolytic and mydriatic. It may have activity as an aphrodisiac.
Impotence (not able to have erections)
The way yohimbine works is not known for sure. It is thought, however, to work by increasing the body’s production of certain chemicals that help produce erections. It does not work in all men who are impotent.
New research that shows it could be an herb with very effective antioxidant potential. Research shows it is a vasodilator, which means that it increases blood flow to the extremities and appendages.
2. Dapoxetine Hydrochloride readily penetrates the (CNS) and produces a complex pattern of responses in lower doses than those required to produce peripheral alpha-adrenergic blockade. These include, anti-diuresis, a general picture of central excitation including elevation of blood pressure and heart rate, increased motor activity, nervousness, irritability and tremor. Sweating, nausea and vomiting are common after parenteral administration of the drug. Also, dizziness, headache skin flushing reported when used orally.
3 .Generally, this drug is not proposed for use in females and certainly must not be used during pregnancy. Neither is this drug proposed for use in pediatric, geriatric or cardio-renal patients with gastric or duodenal ulcer history. Nor should it be used in conjunction with mood- modifying drugs such as antidepressants, or in psychiatric patients in general.
COA:
Item | Requirement | Result |
Appearance | White or almost white crystalline powder | Almost White Powder |
Melting Point | 175°C-185°C | 181.2°C-182.8°C |
Optical Rotation | +128±3 (C=1, CH3OH) | 127.33 |
Loss on Drying | ≤1.0% | 0.20% |
Ignition Residue | ≤0.1% | 0.10% |
Purity | ≥98.5% | 99.47% |
Characteristics: | white powder, odorless, no bitter, used in tablet, capsule and so onFunction: As a new and high-speed SSRi, Dapoxetine is held with short of half-life. It is belonging to the selective 5-hydroxytryptamine reabsorption inhibitor(SSRI), with high effect in premature Ejaculation and ED. | |
Feature: | It is absorbed by stomach, and can be effected after 30-60mins, lasts for several dasy, without side-effect, can't be detected, accompanying light headache, sick, but can disappear soon. | |
Advantage:
1. Method of Analysis for testing our materials are validated to give the re-producible results
2. All the analytical test procedures and manufacturing procedures are well documented and revision is undertaken as per specified protocol.
3. Trend analysis of purified water and final products are maintained.
4. Stability study is a very important area of quality assuance.
5. Paid orders are processed and despatched the same day and delivered within 5-8 working days worldwide.
6. For your convenience, we use discreet packaging and orders are delivered by post and our delivery success rate is 98%.
7. Should you not receive your order for any reason after 20 working days, please contact us where we will be able to assist you locating your order and if it appears tobe lost in the post, we then will then re-send you a replacement immediately.
Packaging and delivery:
1. Mass stock, to make sure delivery promptly every day when the payment is done.
2. Having been engaged in this field for years, we have sophisticated and professional logistics department, which can guarantee safe and speedy delivery.
3. Well-trained and disciplined packing team which is professional enough to provide you a safe package. It also avoid a lot of emergency happen during the delivery so that high customs pass is guaranteed. Unique ways to ship 10grams to 20 kilograms powders(or 100ml to 30 Liter liquids) at one time to your destination.
4. Packing pictures and tacking code are provided within 12 hours as soon as receiving the payment. Updated tracking information will be provided every other day just for you can hold a palm of your package.
5. Perfect after-sale service: Any questions or problems happened after receiving the product, please feel free to contact us. Problems would be solved immediately.
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